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DRUG CLASS:
CD52 inhibitor
DRUG CLASS:
CD52 inhibitor
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Related drugs:
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alemtuzumab (25)
alemtuzumab (1)
ALLO-647 (0)
alemtuzumab (25)
alemtuzumab (1)
ALLO-647 (0)
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Associations
(26)
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No biomarker
Chronic Lymphocytic Leukemia
No biomarker
Chronic Lymphocytic Leukemia
alemtuzumab
Sensitive: A1 - Approval
alemtuzumab
Sensitive
:
A1
alemtuzumab
Sensitive: A1 - Approval
alemtuzumab
Sensitive
:
A1
TP53 mutation
Chronic Lymphocytic Leukemia
TP53 mutation
Chronic Lymphocytic Leukemia
rituximab + alemtuzumab
Sensitive: A2 - Guideline
rituximab + alemtuzumab
Sensitive
:
A2
rituximab + alemtuzumab
Sensitive: A2 - Guideline
rituximab + alemtuzumab
Sensitive
:
A2
TP53 wild-type
Small Lymphocytic Lymphoma
TP53 wild-type
Small Lymphocytic Lymphoma
alemtuzumab
Sensitive: A2 - Guideline
alemtuzumab
Sensitive
:
A2
alemtuzumab
Sensitive: A2 - Guideline
alemtuzumab
Sensitive
:
A2
No biomarker
Peripheral T-cell Lymphoma
No biomarker
Peripheral T-cell Lymphoma
alemtuzumab
Sensitive: A2 - Guideline
alemtuzumab
Sensitive
:
A2
alemtuzumab
Sensitive: A2 - Guideline
alemtuzumab
Sensitive
:
A2
Chr del(17p)
Small Lymphocytic Lymphoma
Chr del(17p)
Small Lymphocytic Lymphoma
alemtuzumab
Sensitive: A2 - Guideline
alemtuzumab
Sensitive
:
A2
alemtuzumab
Sensitive: A2 - Guideline
alemtuzumab
Sensitive
:
A2
TP53 mutation
Small Lymphocytic Lymphoma
TP53 mutation
Small Lymphocytic Lymphoma
alemtuzumab
Sensitive: A2 - Guideline
alemtuzumab
Sensitive
:
A2
alemtuzumab
Sensitive: A2 - Guideline
alemtuzumab
Sensitive
:
A2
Chr del(17p)
Small Lymphocytic Lymphoma
Chr del(17p)
Small Lymphocytic Lymphoma
rituximab + alemtuzumab
Sensitive: A2 - Guideline
rituximab + alemtuzumab
Sensitive
:
A2
rituximab + alemtuzumab
Sensitive: A2 - Guideline
rituximab + alemtuzumab
Sensitive
:
A2
TP53 mutation
Small Lymphocytic Lymphoma
TP53 mutation
Small Lymphocytic Lymphoma
rituximab + alemtuzumab
Sensitive: A2 - Guideline
rituximab + alemtuzumab
Sensitive
:
A2
rituximab + alemtuzumab
Sensitive: A2 - Guideline
rituximab + alemtuzumab
Sensitive
:
A2
Chr del(17p)
Chronic Lymphocytic Leukemia
Chr del(17p)
Chronic Lymphocytic Leukemia
alemtuzumab
Sensitive: A2 - Guideline
alemtuzumab
Sensitive
:
A2
alemtuzumab
Sensitive: A2 - Guideline
alemtuzumab
Sensitive
:
A2
TP53 mutation
Chronic Lymphocytic Leukemia
TP53 mutation
Chronic Lymphocytic Leukemia
alemtuzumab
Sensitive: A2 - Guideline
alemtuzumab
Sensitive
:
A2
alemtuzumab
Sensitive: A2 - Guideline
alemtuzumab
Sensitive
:
A2
Chr del(17p)
Chronic Lymphocytic Leukemia
Chr del(17p)
Chronic Lymphocytic Leukemia
rituximab + alemtuzumab
Sensitive: A2 - Guideline
rituximab + alemtuzumab
Sensitive
:
A2
rituximab + alemtuzumab
Sensitive: A2 - Guideline
rituximab + alemtuzumab
Sensitive
:
A2
No biomarker
Prolymphocytic Leukemia
No biomarker
Prolymphocytic Leukemia
alemtuzumab
Sensitive: A2 - Guideline
alemtuzumab
Sensitive
:
A2
alemtuzumab
Sensitive: A2 - Guideline
alemtuzumab
Sensitive
:
A2
No biomarker
Prolymphocytic Leukemia
No biomarker
Prolymphocytic Leukemia
alemtuzumab
Sensitive: A2 - Guideline
alemtuzumab
Sensitive
:
A2
alemtuzumab
Sensitive: A2 - Guideline
alemtuzumab
Sensitive
:
A2
CD52 expression
Prolymphocytic Leukemia
CD52 expression
Prolymphocytic Leukemia
alemtuzumab
Sensitive: A2 - Guideline
alemtuzumab
Sensitive
:
A2
alemtuzumab
Sensitive: A2 - Guideline
alemtuzumab
Sensitive
:
A2
Chr del(17)(p13.1)
Chronic Lymphocytic Leukemia
Chr del(17)(p13.1)
Chronic Lymphocytic Leukemia
alemtuzumab
Sensitive: C3 – Early Trials
alemtuzumab
Sensitive
:
C3
alemtuzumab
Sensitive: C3 – Early Trials
alemtuzumab
Sensitive
:
C3
Chr del(11)(q22.3)
Chronic Lymphocytic Leukemia
Chr del(11)(q22.3)
Chronic Lymphocytic Leukemia
alemtuzumab
Sensitive: C3 – Early Trials
alemtuzumab
Sensitive
:
C3
alemtuzumab
Sensitive: C3 – Early Trials
alemtuzumab
Sensitive
:
C3
CD123 positive
Acute Myelogenous Leukemia
CD123 positive
Acute Myelogenous Leukemia
alemtuzumab + UCART123
Sensitive: C3 – Early Trials
alemtuzumab + UCART123
Sensitive
:
C3
alemtuzumab + UCART123
Sensitive: C3 – Early Trials
alemtuzumab + UCART123
Sensitive
:
C3
CDKN2A deletion
Prolymphocytic Leukemia
CDKN2A deletion
Prolymphocytic Leukemia
alemtuzumab
Resistant: C4 – Case Studies
alemtuzumab
Resistant
:
C4
alemtuzumab
Resistant: C4 – Case Studies
alemtuzumab
Resistant
:
C4
STAT5B N642H
Prolymphocytic Leukemia
STAT5B N642H
Prolymphocytic Leukemia
alemtuzumab
Resistant: C4 – Case Studies
alemtuzumab
Resistant
:
C4
alemtuzumab
Resistant: C4 – Case Studies
alemtuzumab
Resistant
:
C4
TCL1A rearrangement
Prolymphocytic Leukemia
TCL1A rearrangement
Prolymphocytic Leukemia
alemtuzumab
Resistant: C4 – Case Studies
alemtuzumab
Resistant
:
C4
alemtuzumab
Resistant: C4 – Case Studies
alemtuzumab
Resistant
:
C4
RAD50 Y625
Prolymphocytic Leukemia
RAD50 Y625
Prolymphocytic Leukemia
alemtuzumab
Resistant: C4 – Case Studies
alemtuzumab
Resistant
:
C4
alemtuzumab
Resistant: C4 – Case Studies
alemtuzumab
Resistant
:
C4
ATM D2721N
Prolymphocytic Leukemia
ATM D2721N
Prolymphocytic Leukemia
alemtuzumab
Resistant: C4 – Case Studies
alemtuzumab
Resistant
:
C4
alemtuzumab
Resistant: C4 – Case Studies
alemtuzumab
Resistant
:
C4
PAK4 deletion
Prolymphocytic Leukemia
PAK4 deletion
Prolymphocytic Leukemia
alemtuzumab
Resistant: C4 – Case Studies
alemtuzumab
Resistant
:
C4
alemtuzumab
Resistant: C4 – Case Studies
alemtuzumab
Resistant
:
C4
BRAF V600E
Prolymphocytic Leukemia
BRAF V600E
Prolymphocytic Leukemia
alemtuzumab
Resistant: C4 – Case Studies
alemtuzumab
Resistant
:
C4
alemtuzumab
Resistant: C4 – Case Studies
alemtuzumab
Resistant
:
C4
Chr del(13)(q14)
Chronic Lymphocytic Leukemia
Chr del(13)(q14)
Chronic Lymphocytic Leukemia
alemtuzumab
Sensitive: C4 – Case Studies
alemtuzumab
Sensitive
:
C4
alemtuzumab
Sensitive: C4 – Case Studies
alemtuzumab
Sensitive
:
C4
MYC rearrangement + BCL2 rearrangement
Non-Hodgkin’s Lymphoma
MYC rearrangement + BCL2 rearrangement
Non-Hodgkin’s Lymphoma
ibrutinib + alemtuzumab
Sensitive: D – Preclinical
ibrutinib + alemtuzumab
Sensitive
:
D
ibrutinib + alemtuzumab
Sensitive: D – Preclinical
ibrutinib + alemtuzumab
Sensitive
:
D
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