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Association details:
Biomarker:
TP53 mutation
Cancer:
Chronic Lymphocytic Leukemia
Drug:
Rituxan (rituximab)
(
CD20 inhibitor
) +
Campath (alemtuzumab)
(
CD52 inhibitor
)
Direction:
Sensitive
Evidence:
Evidence Level:
Sensitive: A2 - Guideline
New
Source:
NCCN
Excerpt:
Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma:…CLL/SLL with del(17p)/TP53 mutation...Other recommended regimens...Alemtuzumab ± rituximab
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