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BIOMARKER:
CCND1 expression
i
Other names:
CCND1, BCL1, D11S287E, PRAD1, U21B31, Cyclin D1
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Entrez ID:
595
Related biomarkers:
Expression
Mutation
CNA
Others
‹
ALK fusion + MYC amplification + CCND1 deletion + FGFR3 deletion (1)
ALK positive + MYC amplification + CCND1 deletion (1)
CCND1-H (1)
CCND1 mutation + HR positive (1)
EGFR exon 19 deletion + CCND1 overexpression (1)
EGFR mutation + CCND1 expression + CDKN2A deletion (1)
ER L536H + ER D538G + CCND1 amplification (1)
ER positive + ESR1 mutation + CCND1 amplification (1)
HR positive + CCND1 amplification (1)
ALK fusion + MYC amplification + CCND1 deletion + FGFR3 deletion (1)
ALK positive + MYC amplification + CCND1 deletion (1)
CCND1-H (1)
CCND1 mutation + HR positive (1)
EGFR exon 19 deletion + CCND1 overexpression (1)
EGFR mutation + CCND1 expression + CDKN2A deletion (1)
ER L536H + ER D538G + CCND1 amplification (1)
ER positive + ESR1 mutation + CCND1 amplification (1)
HR positive + CCND1 amplification (1)
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Trials
VERI cancer hierarchy
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CCND1 expression
Non Small Cell Lung Cancer
CCND1 expression
Non Small Cell Lung Cancer
erlotinib
Sensitive: C2 – Inclusion Criteria
erlotinib
Sensitive
:
C2
erlotinib
Sensitive: C2 – Inclusion Criteria
erlotinib
Sensitive
:
C2
CCND1 expression
Diffuse Large B Cell Lymphoma
CCND1 expression
Diffuse Large B Cell Lymphoma
Resistant: C3 – Early Trials
Resistant
:
C3
Resistant: C3 – Early Trials
Resistant
:
C3
CCND1 expression
Mantle Cell Lymphoma
CCND1 expression
Mantle Cell Lymphoma
palbociclib
Sensitive: D – Preclinical
palbociclib
Sensitive
:
D
palbociclib
Sensitive: D – Preclinical
palbociclib
Sensitive
:
D
CCND1 expression
Multiple Myeloma
CCND1 expression
Multiple Myeloma
venetoclax
Sensitive: D – Preclinical
venetoclax
Sensitive
:
D
venetoclax
Sensitive: D – Preclinical
venetoclax
Sensitive
:
D
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