^
    BIOMARKER:

    BTK C481S

    i
    Other names: BTK, Bruton Tyrosine Kinase, Bruton Agammaglobulinemia Tyrosine Kinase, Tyrosine-Protein Kinase BTK, Bruton'S Tyrosine Kinase, B-Cell Progenitor Kinase, AGMX1, ATK, BPK, Tyrosine-Protein Kinase BTK Isoform (Lacking Exon 13 To 17), Dominant-Negative Kinase-Deficient Brutons Tyrosine Kinase, Tyrosine-Protein Kinase BTK Isoform (Lacking Exon 14), Truncated Bruton Agammaglobulinemia Tyrosine Kinase, Agammaglobulinaemia Tyrosine Kinase, Agammaglobulinemia Tyrosine Kinase, PSCTK1, IGHD3, IMD1, XLA, AT
    Entrez ID:
    695
    Related biomarkers:
    Expression
    Mutation
    BTK C481S
    CLL
    acalabrutinib
    Resistant: A2 - Guideline
    BTK C481S
    CLL
    LOXO-305
    Sensitive: C3 – Early Trials
    BTK C481S
    CLL
    ibrutinib
    Resistant: C3 – Early Trials
    BTK C481S
    Mantle Cell Lymphoma
    TG-1701
    Sensitive: D – Preclinical
    BTK C481S
    CLL
    GS-9973
    Sensitive: D – Preclinical
    BTK C481S
    Mantle Cell Lymphoma
    ibrutinib
    Resistant: D – Preclinical
    BTK C481S
    Mantle Cell Lymphoma
    SRX3262
    Sensitive: D – Preclinical
    BTK C481S
    CLL
    SNS-062
    Sensitive: D – Preclinical