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BIOMARKER:
BRCA2 biallelic inactivation
i
Other names:
BRCA2, BRCC2, FACD, FAD, FAD1, FANCD, FANCD1, Breast cancer 2, early onset
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Entrez ID:
675
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
BRCA2 mutation (200)
BRCA wild-type (19)
BRCA1 mutation + BRCA2 mutation (4)
BRCA2 A902fs*2 (3)
BRCA2 mutation + CHEK2 mutation (2)
BRCA2 mutation + TP53 mutation (2)
BRCA2 rearrangement (2)
APC mutation + BRCA2 mutation (1)
BRCA2 1153insT (1)
BRCA2 5396insC (1)
BRCA2 I2315T (1)
BRCA2 L557* (1)
BRCA2 N255fs + D252fs (1)
BRCA2 Y1655* + TP53 mutation (1)
BRCA2 mutation + ATM mutation (1)
BRCA2 mutation + CDK12 mutation (1)
BRCA2 mutation + SPOP mutation (1)
BRCA2 mutation + TP53 D816Y (1)
CHEK2 mutation + ATM mutation + BRCA2 mutation (1)
EGFR exon 19 deletion + BRCA2 mutation (1)
BRCA2 E260fs (0)
BRCA2 N255_R259delinsIK (0)
BRCA2 N255fs (0)
BRCA2 N255fs + BRCA2 N255_R259delinsIK + BRCA2 E260fs (0)
BRCA2 mutation (200)
BRCA wild-type (19)
BRCA1 mutation + BRCA2 mutation (4)
BRCA2 A902fs*2 (3)
BRCA2 mutation + CHEK2 mutation (2)
BRCA2 mutation + TP53 mutation (2)
BRCA2 rearrangement (2)
APC mutation + BRCA2 mutation (1)
BRCA2 1153insT (1)
BRCA2 5396insC (1)
BRCA2 I2315T (1)
BRCA2 L557* (1)
BRCA2 N255fs + D252fs (1)
BRCA2 Y1655* + TP53 mutation (1)
BRCA2 mutation + ATM mutation (1)
BRCA2 mutation + CDK12 mutation (1)
BRCA2 mutation + SPOP mutation (1)
BRCA2 mutation + TP53 D816Y (1)
CHEK2 mutation + ATM mutation + BRCA2 mutation (1)
EGFR exon 19 deletion + BRCA2 mutation (1)
BRCA2 E260fs (0)
BRCA2 N255_R259delinsIK (0)
BRCA2 N255fs (0)
BRCA2 N255fs + BRCA2 N255_R259delinsIK + BRCA2 E260fs (0)
›
Associations
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Trials
VERI cancer hierarchy
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BRCA2 biallelic inactivation
Prostate Cancer
BRCA2 biallelic inactivation
Prostate Cancer
niraparib
Sensitive: C3 – Early Trials
niraparib
Sensitive
:
C3
niraparib
Sensitive: C3 – Early Trials
niraparib
Sensitive
:
C3
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