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BIOMARKER:
BRCA1 mutation + TMB-H
i
Other names:
TMB | Tumor Mutational Burden, BRCA1, BRCC1, PPP1R53, RNF53, Breast cancer 1, early onset
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Entrez ID:
672
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
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BRCA1 fusion (0)
BRCA1 fusion (0)
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VERI cancer hierarchy
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BRCA1 mutation + TMB-H
Non Small Cell Lung Cancer
BRCA1 mutation + TMB-H
Non Small Cell Lung Cancer
Immunotherapy
Resistant: C3 – Early Trials
Immunotherapy
Resistant
:
C3
Immunotherapy
Resistant: C3 – Early Trials
Immunotherapy
Resistant
:
C3
BRCA1 mutation + TMB-H
Pancreatic Adenocarcinoma
BRCA1 mutation + TMB-H
Pancreatic Adenocarcinoma
pembrolizumab + olaparib
Sensitive: C4 – Case Studies
pembrolizumab + olaparib
Sensitive
:
C4
pembrolizumab + olaparib
Sensitive: C4 – Case Studies
pembrolizumab + olaparib
Sensitive
:
C4
BRCA1 mutation + TMB-H
Pancreatic Ductal Adenocarcinoma
BRCA1 mutation + TMB-H
Pancreatic Ductal Adenocarcinoma
pembrolizumab + olaparib
Sensitive: C4 – Case Studies
pembrolizumab + olaparib
Sensitive
:
C4
pembrolizumab + olaparib
Sensitive: C4 – Case Studies
pembrolizumab + olaparib
Sensitive
:
C4
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