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BIOMARKER:
BRAF mutation + NF1 mutation
i
Other names:
BRAF, B-raf proto-oncogene, B-raf proto-oncogene, Serine/threonine kinase, V-Raf murine sarcoma viral oncogene homolog B, Serine/threonine-protein kinase B-Raf, Proto-oncogene B-Raf, BRAF1, RAFB1, B-raf proto-oncogene Serine/threonine-protein kinase, Murine sarcoma viral (V-Raf) oncogene homolog B1, B-raf serine/threonine-protein, 94 KDa B-raf protein, B-RAF1, NFNS, NF1, Neurofibromin 1, Neurofibromatosis-Related Protein NF-1, Truncated Neurofibromin 1
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Entrez ID:
673
;
4763
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
KIAA1549-BRAF fusion (10)
BRAF fusion (9)
AGK-BRAF fusion (5)
SKAP2-BRAF fusion (4)
TARDBP-BRAF fusion (4)
FKBP15-BRAF fusion (3)
PPFIBP2-BRAF fusion (3)
CUL1-BRAF fusion (2)
SLC45A3-BRAF fusion (2)
SND1-BRAF fusion (2)
BRAF-MAD1L1 fusion (1)
BRAF-ZC3H7A fusion (1)
CUX1-BRAF fusion (1)
EXOC4-BRAF fusion (1)
NRF1-BRAF fusion (1)
TRIM33-BRAF fusion (1)
ZKSCAN1-BRAF fusion (1)
KIAA1549-BRAF fusion (10)
BRAF fusion (9)
AGK-BRAF fusion (5)
SKAP2-BRAF fusion (4)
TARDBP-BRAF fusion (4)
FKBP15-BRAF fusion (3)
PPFIBP2-BRAF fusion (3)
CUL1-BRAF fusion (2)
SLC45A3-BRAF fusion (2)
SND1-BRAF fusion (2)
BRAF-MAD1L1 fusion (1)
BRAF-ZC3H7A fusion (1)
CUX1-BRAF fusion (1)
EXOC4-BRAF fusion (1)
NRF1-BRAF fusion (1)
TRIM33-BRAF fusion (1)
ZKSCAN1-BRAF fusion (1)
›
Associations
News
Trials
VERI cancer hierarchy
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BRAF mutation + NF1 mutation
Melanoma
BRAF mutation + NF1 mutation
Melanoma
selumetinib
Resistant: C3 – Early Trials
selumetinib
Resistant
:
C3
selumetinib
Resistant: C3 – Early Trials
selumetinib
Resistant
:
C3
BRAF mutation + NF1 mutation
Melanoma
BRAF mutation + NF1 mutation
Melanoma
BRAF inhibitor + MEK inhibitor
Sensitive: D – Preclinical
BRAF inhibitor + MEK inhibitor
Sensitive
:
D
BRAF inhibitor + MEK inhibitor
Sensitive: D – Preclinical
BRAF inhibitor + MEK inhibitor
Sensitive
:
D
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