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BIOMARKER:
BRAF mutation + NF1 mutation
i
Other names:
BRAF, B-raf proto-oncogene, B-raf proto-oncogene, Serine/threonine kinase, V-Raf murine sarcoma viral oncogene homolog B, Serine/threonine-protein kinase B-Raf, Proto-oncogene B-Raf, BRAF1, RAFB1, B-raf proto-oncogene Serine/threonine-protein kinase, Murine sarcoma viral (V-Raf) oncogene homolog B1, B-raf serine/threonine-protein, 94 KDa B-raf protein, B-RAF1, NFNS, NF1, Neurofibromin 1, Neurofibromatosis-Related Protein NF-1, Truncated Neurofibromin 1
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Entrez ID:
673
;
4763
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
BRAF positive (1)
NF1 overexpression (1)
NF1 underexpression (1)
BRAF positive (1)
NF1 overexpression (1)
NF1 underexpression (1)
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Associations
News
Trials
VERI cancer hierarchy
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BRAF mutation + NF1 mutation
Melanoma
BRAF mutation + NF1 mutation
Melanoma
selumetinib
Resistant: C3 – Early Trials
selumetinib
Resistant
:
C3
selumetinib
Resistant: C3 – Early Trials
selumetinib
Resistant
:
C3
BRAF mutation + NF1 mutation
Melanoma
BRAF mutation + NF1 mutation
Melanoma
BRAF inhibitor + MEK inhibitor
Sensitive: D – Preclinical
BRAF inhibitor + MEK inhibitor
Sensitive
:
D
BRAF inhibitor + MEK inhibitor
Sensitive: D – Preclinical
BRAF inhibitor + MEK inhibitor
Sensitive
:
D
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