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BIOMARKER:
AXL overexpression
i
Other names:
AXL Receptor Tyrosine Kinase, Tyrosine Protein Kinase Receptor UFO, AXL Oncogene, AXL Transforming Sequence Gene, Tyro7
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Entrez ID:
558
Related biomarkers:
Expression
Mutation
CNA
Others
‹
AXL elevation (2)
AXL expression + EGFR mutation (2)
AXL-L (2)
AXL elevation + GAS6 elevation (1)
AXL overexpression + EGFR mutation (1)
AXL overexpression + KRAS G12C (1)
AXL underexpression + EGFR mutation (1)
HER-2 amplification + AXL expression (1)
KRAS mutation + STK11 mutation + AXL expression (1)
AXL elevation (2)
AXL expression + EGFR mutation (2)
AXL-L (2)
AXL elevation + GAS6 elevation (1)
AXL overexpression + EGFR mutation (1)
AXL overexpression + KRAS G12C (1)
AXL underexpression + EGFR mutation (1)
HER-2 amplification + AXL expression (1)
KRAS mutation + STK11 mutation + AXL expression (1)
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Associations
News
Trials
VERI cancer hierarchy
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AXL overexpression
Colorectal Cancer
AXL overexpression
Colorectal Cancer
cetuximab
Resistant: C3 – Early Trials
cetuximab
Resistant
:
C3
cetuximab
Resistant: C3 – Early Trials
cetuximab
Resistant
:
C3
AXL overexpression
Clear Cell Renal Cell Carcinoma
AXL overexpression
Clear Cell Renal Cell Carcinoma
nivolumab
Resistant: C3 – Early Trials
nivolumab
Resistant
:
C3
nivolumab
Resistant: C3 – Early Trials
nivolumab
Resistant
:
C3
AXL overexpression
Non Small Cell Lung Cancer
AXL overexpression
Non Small Cell Lung Cancer
osimertinib
Resistant: C3 – Early Trials
osimertinib
Resistant
:
C3
osimertinib
Resistant: C3 – Early Trials
osimertinib
Resistant
:
C3
AXL overexpression
Non Small Cell Lung Cancer
AXL overexpression
Non Small Cell Lung Cancer
afatinib
Resistant: D – Preclinical
afatinib
Resistant
:
D
afatinib
Resistant: D – Preclinical
afatinib
Resistant
:
D
AXL overexpression
Non Small Cell Lung Cancer
AXL overexpression
Non Small Cell Lung Cancer
ASP8273
Sensitive: D – Preclinical
ASP8273
Sensitive
:
D
ASP8273
Sensitive: D – Preclinical
ASP8273
Sensitive
:
D
AXL overexpression
Ovarian Cancer
AXL overexpression
Ovarian Cancer
VS-6766 + BGB324
Sensitive: D – Preclinical
VS-6766 + BGB324
Sensitive
:
D
VS-6766 + BGB324
Sensitive: D – Preclinical
VS-6766 + BGB324
Sensitive
:
D
AXL overexpression
Squamous Cell Carcinoma of Head and Neck
AXL overexpression
Squamous Cell Carcinoma of Head and Neck
cetuximab
Resistant: D – Preclinical
cetuximab
Resistant
:
D
cetuximab
Resistant: D – Preclinical
cetuximab
Resistant
:
D
AXL overexpression
Melanoma
AXL overexpression
Melanoma
BGB324
Sensitive: D – Preclinical
BGB324
Sensitive
:
D
BGB324
Sensitive: D – Preclinical
BGB324
Sensitive
:
D
AXL overexpression
Melanoma
AXL overexpression
Melanoma
vemurafenib + BGB324
Sensitive: D – Preclinical
vemurafenib + BGB324
Sensitive
:
D
vemurafenib + BGB324
Sensitive: D – Preclinical
vemurafenib + BGB324
Sensitive
:
D
AXL overexpression
Adenoid Cystic Carcinoma
AXL overexpression
Adenoid Cystic Carcinoma
ADCT-601
Sensitive: D – Preclinical
ADCT-601
Sensitive
:
D
ADCT-601
Sensitive: D – Preclinical
ADCT-601
Sensitive
:
D
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