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DRUG:

elesclomol (STA-4783)

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News alerts, weekly reports and conference planners

Company:

Madrigal Pharma

Drug class:

Apoptosis stimulant, Reactive oxygen species stimulant, HSP70 stimulant

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GNA11 mutation	Uveal Melanoma	GNA11 mutation	Uveal Melanoma	binimetinib + STA-4783 Sensitive: D – Preclinical binimetinib + STA-4783 Sensitive : D	binimetinib + STA-4783 Sensitive: D – Preclinical binimetinib + STA-4783 Sensitive : D
GNAQ mutation	Uveal Melanoma	GNAQ mutation	Uveal Melanoma	binimetinib + STA-4783 Sensitive: D – Preclinical binimetinib + STA-4783 Sensitive : D	binimetinib + STA-4783 Sensitive: D – Preclinical binimetinib + STA-4783 Sensitive : D
GNA11 mutation	Uveal Melanoma	GNA11 mutation	Uveal Melanoma	STA-4783 Sensitive: D – Preclinical STA-4783 Sensitive : D	STA-4783 Sensitive: D – Preclinical STA-4783 Sensitive : D
GNAQ mutation	Uveal Melanoma	GNAQ mutation	Uveal Melanoma	STA-4783 Sensitive: D – Preclinical STA-4783 Sensitive : D	STA-4783 Sensitive: D – Preclinical STA-4783 Sensitive : D
MPZL3 overexpression	Breast Cancer	MPZL3 overexpression	Breast Cancer	STA-4783 Resistant: D – Preclinical STA-4783 Resistant : D	STA-4783 Resistant: D – Preclinical STA-4783 Resistant : D