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BIOMARKER:

ALK mutation

i
Other names: NBLST3, CD246, Anaplastic Lymphoma Kinase, Anaplastic Lymphoma Kinase (Ki-1), CD246 Antigen, Mutant Anaplastic Lymphoma Kinase, ALK, ALK Receptor Tyrosine Kinase, Anaplastic Lymphoma Receptor Tyrosine Kinase, ALK Tyrosine Kinase Receptor
Entrez ID:
ALK mutation
Non Small Cell Lung Cancer
pembrolizumab
Sensitive
:
A1
ALK mutation
Lung Non-Squamous Non-Small Cell Cancer
nivolumab
Sensitive
:
A1
ALK mutation
Non Small Cell Lung Cancer
ceritinib
Sensitive
:
A2
ALK mutation
Non Small Cell Lung Cancer
lorlatinib
Sensitive
:
A2
ALK mutation
Non Small Cell Lung Cancer
sintilimab
Sensitive
:
C2
ALK mutation
Lung Non-Squamous Non-Small Cell Cancer
anlotinib
Sensitive
:
C2
ALK mutation
Non Small Cell Lung Cancer
EGFR inhibitor
Sensitive
:
C3
ALK mutation
Non Small Cell Lung Cancer
ALK inhibitor
Sensitive
:
C3
ALK mutation
Non Small Cell Lung Cancer
Tyrosine kinase inhibitor
Sensitive
:
C3
ALK mutation
Non Small Cell Lung Cancer
alectinib
Sensitive
:
C3
ALK mutation
Non Small Cell Lung Cancer
crizotinib + alectinib
Sensitive
:
C3
ALK mutation
Non Small Cell Lung Cancer
nivolumab + ipilimumab
Sensitive
:
C3
ALK mutation
Melanoma
entrectinib
Resistant
:
C4
ALK mutation
Melanoma
crizotinib
Sensitive
:
C4