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BIOMARKER:
AKT1 mutation
i
Other names:
AKT1, AKT, PKB, PRKBA, RAC, V-akt murine thymoma viral oncogene homolog 1
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Entrez ID:
207
Related biomarkers:
Expression
Mutation
CNA
Others
‹
AKT1 E17K + HR positive (2)
AKT1 mutation + ER positive (2)
AKT1 mutation + HR positive (2)
AKT1 mutation + ER negative (1)
EGFR V843I + KRAS G13D + AKT1 E17K + PD-L1 overexpression (1)
AKT1 E17K + CTNNB1 G34R + ER Y537S + MSI-H (0)
AKT1 E17K + HR positive (2)
AKT1 mutation + ER positive (2)
AKT1 mutation + HR positive (2)
AKT1 mutation + ER negative (1)
EGFR V843I + KRAS G13D + AKT1 E17K + PD-L1 overexpression (1)
AKT1 E17K + CTNNB1 G34R + ER Y537S + MSI-H (0)
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Associations
News
Trials
VERI cancer hierarchy
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AKT1 mutation
Triple Negative Breast Cancer
AKT1 mutation
Triple Negative Breast Cancer
RG7440
Sensitive: B - Late Trials
RG7440
Sensitive
:
B
RG7440
Sensitive: B - Late Trials
RG7440
Sensitive
:
B
AKT1 mutation
Colorectal Cancer
AKT1 mutation
Colorectal Cancer
atezolizumab + cobimetinib
Sensitive: B - Late Trials
atezolizumab + cobimetinib
Sensitive
:
B
atezolizumab + cobimetinib
Sensitive: B - Late Trials
atezolizumab + cobimetinib
Sensitive
:
B
AKT1 mutation
Breast Cancer
AKT1 mutation
Breast Cancer
ribociclib
Sensitive: B - Late Trials
ribociclib
Sensitive
:
B
ribociclib
Sensitive: B - Late Trials
ribociclib
Sensitive
:
B
AKT1 mutation
Endometrial Cancer
AKT1 mutation
Endometrial Cancer
temsirolimus
Sensitive: C3 – Early Trials
temsirolimus
Sensitive
:
C3
temsirolimus
Sensitive: C3 – Early Trials
temsirolimus
Sensitive
:
C3
AKT1 mutation
Solid Tumor
AKT1 mutation
Solid Tumor
ARQ 751
Sensitive: C3 – Early Trials
ARQ 751
Sensitive
:
C3
ARQ 751
Sensitive: C3 – Early Trials
ARQ 751
Sensitive
:
C3
AKT1 mutation
Prostate Cancer
AKT1 mutation
Prostate Cancer
capivasertib
Sensitive: D – Preclinical
capivasertib
Sensitive
:
D
capivasertib
Sensitive: D – Preclinical
capivasertib
Sensitive
:
D
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