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BIOMARKER:

AKT1 mutation

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Entrez ID:

Related biomarkers:

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AKT1 amplification (1)

AKT1 amplification (1)

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AKT1 mutation	Triple Negative Breast Cancer	AKT1 mutation	Triple Negative Breast Cancer	RG7440 Sensitive: B - Late Trials RG7440 Sensitive : B	RG7440 Sensitive: B - Late Trials RG7440 Sensitive : B
AKT1 mutation	Colorectal Cancer	AKT1 mutation	Colorectal Cancer	atezolizumab + cobimetinib Sensitive: B - Late Trials atezolizumab + cobimetinib Sensitive : B	atezolizumab + cobimetinib Sensitive: B - Late Trials atezolizumab + cobimetinib Sensitive : B
AKT1 mutation	Breast Cancer	AKT1 mutation	Breast Cancer	ribociclib Sensitive: B - Late Trials ribociclib Sensitive : B	ribociclib Sensitive: B - Late Trials ribociclib Sensitive : B
AKT1 mutation	Endometrial Cancer	AKT1 mutation	Endometrial Cancer	temsirolimus Sensitive: C3 – Early Trials temsirolimus Sensitive : C3	temsirolimus Sensitive: C3 – Early Trials temsirolimus Sensitive : C3
AKT1 mutation	Solid Tumor	AKT1 mutation	Solid Tumor	ARQ 751 Sensitive: C3 – Early Trials ARQ 751 Sensitive : C3	ARQ 751 Sensitive: C3 – Early Trials ARQ 751 Sensitive : C3
AKT1 mutation	Prostate Cancer	AKT1 mutation	Prostate Cancer	capivasertib Sensitive: D – Preclinical capivasertib Sensitive : D	capivasertib Sensitive: D – Preclinical capivasertib Sensitive : D