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BIOMARKER:
AKT1 mutation + mTOR mutation
i
Other names:
AKT1, AKT, PKB, PRKBA, RAC, V-akt murine thymoma viral oncogene homolog 1, mTOR, Mechanistic Target Of Rapamycin Kinase, Mammalian Target Of Rapamycin, Rapamycin And FKBP12 Target 1, FK506-Binding Protein 12-Rapamycin Complex-Associated Protein 1, Mechanistic Target Of Rapamycin (Serine/Threonine Kinase), FK506 Binding Protein 12-Rapamycin Associated Protein 2, FKBP12-Rapamycin Complex-Associated Protein 1, Serine/Threonine-Protein Kinase MTOR, Rapamycin Associated Protein FRAP2, FKBP-Rapamycin
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Entrez ID:
207
;
2475
Related biomarkers:
Expression
Mutation
CNA
Others
‹
AKT1 E17K (12)
AKT1 mutation (6)
MTOR F2108L (5)
MTOR mutation (5)
MTOR S2215Y (3)
AKT1 Q79K (2)
MTOR A2034V (2)
MTOR E2014K (2)
MTOR H1968Y (2)
MTOR M2327I (2)
MTOR P2213S (2)
AKT1 E17K + BRAF V600 (1)
AKT1 mutation + AR mutation (1)
PIK3CA G1049R + AKT1 E17K (1)
PIK3CA mutation + AKT1 mutation + PTEN mutation (1)
MTOR E1799K (1)
MTOR E2419K (1)
MTOR L1433S + EGFR L858R + EGFR T790M (1)
MTOR Q2223K (1)
HER-2 negative + HR positive + AKT1 mutation (0)
AKT1 E17K (12)
AKT1 mutation (6)
MTOR F2108L (5)
MTOR mutation (5)
MTOR S2215Y (3)
AKT1 Q79K (2)
MTOR A2034V (2)
MTOR E2014K (2)
MTOR H1968Y (2)
MTOR M2327I (2)
MTOR P2213S (2)
AKT1 E17K + BRAF V600 (1)
AKT1 mutation + AR mutation (1)
PIK3CA G1049R + AKT1 E17K (1)
PIK3CA mutation + AKT1 mutation + PTEN mutation (1)
MTOR E1799K (1)
MTOR E2419K (1)
MTOR L1433S + EGFR L858R + EGFR T790M (1)
MTOR Q2223K (1)
HER-2 negative + HR positive + AKT1 mutation (0)
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AKT1 mutation + mTOR mutation
Leiomyosarcoma
AKT1 mutation + mTOR mutation
Leiomyosarcoma
CB-228
Sensitive: C3 – Early Trials
CB-228
Sensitive
:
C3
CB-228
Sensitive: C3 – Early Trials
CB-228
Sensitive
:
C3
AKT1 mutation + mTOR mutation
Endometrial Cancer
AKT1 mutation + mTOR mutation
Endometrial Cancer
CB-228
Sensitive: C4 – Case Studies
CB-228
Sensitive
:
C4
CB-228
Sensitive: C4 – Case Studies
CB-228
Sensitive
:
C4
AKT1 mutation + mTOR mutation
Breast Cancer
AKT1 mutation + mTOR mutation
Breast Cancer
CB-228
Sensitive: C4 – Case Studies
CB-228
Sensitive
:
C4
CB-228
Sensitive: C4 – Case Studies
CB-228
Sensitive
:
C4
AKT1 mutation + mTOR mutation
Solid Tumor
AKT1 mutation + mTOR mutation
Solid Tumor
CB-228
Sensitive: C4 – Case Studies
CB-228
Sensitive
:
C4
CB-228
Sensitive: C4 – Case Studies
CB-228
Sensitive
:
C4
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