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BIOMARKER:
TMB-H + PD-L1 overexpression
i
Other names:
PD-L1, CD274, HPD-L1, PD-L1, B7H1, PDL1, Programmed death ligand 1, B7-H1, B7-H, PDCD1L1, PDCD1LG1, PDCD1 Ligand 1, B7 homolog 1, CD274 Antigen, Programmed cell death 1 ligand 1, CD274 molecule, TMB | Tumor Mutational Burden
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Entrez ID:
29126
Related biomarkers:
Expression
Mutation
CNA
Others
‹
NF1 L581Ffs*6 + KRAS A146P + NRAS Q61K + TP53 R175H + PD-L1 T290M (1)
PD-L1 rs1411262 (1)
PD-L1 rs2297136 (1)
PD-L1 rs4143815 (1)
PD-L1 rs822339 (1)
PD-L1 T290M (0)
PD-L1 mutation (0)
NF1 L581Ffs*6 + KRAS A146P + NRAS Q61K + TP53 R175H + PD-L1 T290M (1)
PD-L1 rs1411262 (1)
PD-L1 rs2297136 (1)
PD-L1 rs4143815 (1)
PD-L1 rs822339 (1)
PD-L1 T290M (0)
PD-L1 mutation (0)
›
Associations
(7)
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Trials
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Latest
almost3years
MORE w/ #ASCO21 abstract released today: Landscape of KRASG12C, associated genomic alterations, and interrelation with immuno-oncology (IO) biomarkers. Relationship to high TMB and PD-L1 overexpression. #Colorectal #CRCSM @agrothey @JeanneTie https://t.co/9D9lPl59AJ (@fireflyann)
almost 3 years ago
IO biomarker
|
PD-L1 (Programmed death ligand 1) • KRAS (KRAS proto-oncogene GTPase) • TMB (Tumor Mutational Burden)
|
TMB-H • PD-L1 overexpression • KRAS G12C • KRAS G12 • TMB-H + PD-L1 overexpression
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