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BIOMARKER:
MET fusion
i
Other names:
DFNB97, AUTS9, RCCP2, C-Met, HGFR, HGF Receptor, Met Proto-Oncogene, HGF/SF Receptor, Proto-Oncogene C-Met, Scatter Factor Receptor, Tyrosine-Protein Kinase Met, Hepatocyte Growth Factor Receptor, MET, MET Proto-Oncogene, Receptor Tyrosine Kinase
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News alerts, weekly reports and conference planners
Entrez ID:
4233
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
MET exon 14 mutation (33)
MET mutation (13)
MET H1094Y (3)
MET N375S (3)
EGFR mutation + MET mutation (2)
MET D1010N (2)
MET D1228N (2)
MET D1228V (2)
MET F1200I (2)
MET exon 14 mutation + EGFR exon 20 insertion (2)
EGFR T790M + MET mutation (1)
EGFR exon 21 deletion + EGFR L858R + MET Exon 14 mutation (1)
EGFR mutation + MET Y1003N (1)
EGFR wild-type + MET wild-type (1)
MET D1010H (1)
MET D1010Y (1)
MET D1028N (1)
MET R1004G (1)
MET Y1003C (1)
MET Y1021H (1)
MET Y1230C (1)
MET exon 14 mutation + KRAS G12A (1)
MET exon 14 mutation + TP53 mutation (1)
MET mutation + AXL mutation (1)
MET D1228Y (0)
MET exon 14 skipping mutation + EGFR G709T (0)
MET D1228H (0)
MET Y1230C (0)
ROS rearrangement + MET D1246N (0)
MET exon 14 mutation (33)
MET mutation (13)
MET H1094Y (3)
MET N375S (3)
EGFR mutation + MET mutation (2)
MET D1010N (2)
MET D1228N (2)
MET D1228V (2)
MET F1200I (2)
MET exon 14 mutation + EGFR exon 20 insertion (2)
EGFR T790M + MET mutation (1)
EGFR exon 21 deletion + EGFR L858R + MET Exon 14 mutation (1)
EGFR mutation + MET Y1003N (1)
EGFR wild-type + MET wild-type (1)
MET D1010H (1)
MET D1010Y (1)
MET D1028N (1)
MET R1004G (1)
MET Y1003C (1)
MET Y1021H (1)
MET Y1230C (1)
MET exon 14 mutation + KRAS G12A (1)
MET exon 14 mutation + TP53 mutation (1)
MET mutation + AXL mutation (1)
MET D1228Y (0)
MET exon 14 skipping mutation + EGFR G709T (0)
MET D1228H (0)
MET Y1230C (0)
ROS rearrangement + MET D1246N (0)
›
Related tests:
Oncomine™ Dx Target Test (10)
Oncomine™ Dx Target Test (10)
Associations
(2)
News
Trials
Search handles
@AndresFCardonaZ
@StephenVLiu
@VivekSubbiah
@chulkimMD
Search handles
@AndresFCardonaZ
@StephenVLiu
@VivekSubbiah
@chulkimMD
Filter by
Latest
10ms
A report on MET fusions in NSCLC published @JTOonline by Dr. Jurgen Wolf & colleagues Prevalence approximately 0.29% Five different fusion partners identified and responses seen with MET TKI Tx Emerging biomarker in NSCLC and beyond! https://t.co/TB4rGReynn (@chulkimMD)
10 months ago
MET fusion
over1year
Case report @ClinicalLung showing a novel PRKAR1A:MET fusion in NSCLC with a dramatic response to crizotinib. #MET fusions are rare with multiple different fusion partners described and they may not all be equally actionable. More work needed here. https://t.co/WpZM1Cp17h (@StephenVLiu)
over 1 year ago
Clinical
|
PRKAR1A (Protein Kinase CAMP-Dependent Type I Regulatory Subunit Alpha)
|
MET fusion
|
Xalkori (crizotinib)
almost3years
Acquired Tertiary MET Resistance (MET D1228N and a Novel LSM8-MET Fusion) to Selpercatinib and Capmatinib in a Patient With KIF5B-RET–positive NSCLC With Secondary MET Amplification as Initial Resistance to Selpercatinib @JTOonline https://t.co/ZCmqRnarbu (@VivekSubbiah)
almost 3 years ago
Clinical
|
MET (MET proto-oncogene, receptor tyrosine kinase) • KIF5B (Kinesin Family Member 5B)
|
MET amplification • MET D1228N • MET fusion
|
Retevmo (selpercatinib) • Tabrecta (capmatinib)
almost3years
⭐️Acquired Tertiary MET Resistance (MET D1228N and a Novel LSM8-MET Fusion) to Selpercatinib and Capmatinib in a Patient With KIF5B-RET–positive NSCLC With Secondary MET Amplification as Initial Resistance to Selpercatinib @JTOonline @oncoOuLungCA https://t.co/PoShj6K8vu (@VivekSubbiah)
almost 3 years ago
Clinical
|
MET (MET proto-oncogene, receptor tyrosine kinase) • KIF5B (Kinesin Family Member 5B)
|
MET amplification • MET D1228N • MET fusion
|
Retevmo (selpercatinib) • Tabrecta (capmatinib)
3years
Tepotinib Efficacy in a Patient with Non‐Small Cell Lung Cancer with Brain Metastasis Harboring an HLA‐DRB1‐MET Gene Fusion https://t.co/YF1ezdaCDP (@AndresFCardonaZ)
3 years ago
Clinical
|
MET (MET proto-oncogene, receptor tyrosine kinase) • HLA-DRB1 (Major Histocompatibility Complex, Class II, DR Beta 1)
|
MET fusion
|
Tepmetko (tepotinib)
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