TEST:

RNAscope™ ISH Probe High Risk HPV

RNAscope in situ hybridization (ISH) gives anatomic pathologists a direct method for detection of active HPV through interrogation of E6/E7 viral oncogene mRNA, targets that provide unequivocal evidence of HPV in contrast to p16, a surrogate marker, which is upregulated by HPV as well as other non-HPV pathways