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Laboratory Developed Test
Related tests:
OncoDEEP analyses solid biopsies by combining next-generation sequencing (313 genes), IHCs to study protein expression and additional tests. This complete tumour profiling allows to predict patient response to approved or experimental hormonal therapies, targeted drugs, immunotherapies and chemotherapies. The NGS panel is accurately designed according to oncologists’ needs in their current practice. Importantly, it includes an accurate determination of MSI, TMB and LOH. The NGS panel is regularly updated based on new findings reported in the literature in order to provide patients with the most cost-effective solution. NRTK testing is included in OncoDEEP for some cancer types and it can be ordered also as a standalone test.
Breast Cancer, Colorectal Cancer, Glioblastoma, Lung Adenocarcinoma, Non Small Cell Lung Cancer, Ovarian Cancer, Pancreatic Cancer, Prostate Cancer, Triple Negative Breast Cancer, Urothelial Cancer
ALK (Anaplastic lymphoma kinase), ARID1A (AT-rich interaction domain 1A), BRAF (B-raf proto-oncogene), BRCA1 (Breast cancer 1, early onset), BRCA2 (Breast cancer 2, early onset), EGFR (Epidermal growth factor receptor)
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5-fluorouracil, Alecensa (alectinib), Alunbrig (brigatinib), Erbitux (cetuximab), Gavreto (pralsetinib), Gilotrif (afatinib), Herceptin (trastuzumab), Kadcyla (ado-trastuzumab emtansine), Keytruda (pembrolizumab), Libtayo (cemiplimab-rwlc), Lorbrena (lorlatinib), Lynparza (olaparib), Mekinist (trametinib), Nerlynx (neratinib), Opdivo (nivolumab), Pemazyre (pemigatinib), Perjeta (pertuzumab), Piqray (alpelisib), Retevmo (selpercatinib), Rozlytrek (entrectinib), Tabrecta (capmatinib), Tafinlar (dabrafenib), Tagrisso (osimertinib), Tecentriq (atezolizumab), Vitrakvi (larotrectinib), Xalkori (crizotinib), Zykadia (ceritinib), anastrozole, capecitabine, epirubicin, erlotinib, everolimus, exemestane, gefitinib, gemcitabine, lapatinib, letrozole, pemetrexed, tamoxifen
Next-Generation Sequencing (NGS)