TEST:

Nu.Q® Lung Cancer Test

"VolitionRx Limited...today announces the results of a study which shows that an automated Nu.Q® Cancer immunoassay test in development detected a range of 21 different cancers. This could potentially be used as a standalone pan-cancer test or, given its low false positive rate among healthy people, be licensed out for use in conjunction with other liquid biopsy technologies to improve accuracy."

"VolitionRx Limited...announces first patient enrollment in a clinical study evaluating the company's proprietary Nu.Q Cancer technology for distinguishing between malignant and benign pulmonary nodules in patients undergoing low-dose computed tomography (LDCT) screening for lung cancer....We are delighted to have recruited the first patient into our 500-patient prospective validation study.'"

"VolitionRx...today announces that it has signed an agreement with a leading pharmaceutical company to utilize Volition's Nu.Q® Discover biomarkers in a longitudinal Phase 1/2b study. The Nu.Q® Discover program provides drug developers and scientists with a range of state-of-the-art assays for rapid epigenetic profiling in disease model development, preclinical testing, and clinical studies from discovery to market ready...Following a successful pilot study, two of Volition's Nu.Q® Discover assays were selected for use in this study. It is expected to be completed over a 12-18 month period, generating significant revenue for Volition for this study alone, with further projects being discussed."

"VolitionRx Limited...today announced the results of a large-scale study which shows that its Nu.Q® Cancer Test differentiated between malignant and benign pulmonary nodules, found by Low Dose CT (LDCT) scan, in patients suspected of lung cancer...The 800-patient prospective study was led by Professor Jin-Shing Chen and his team at National Taiwan University Hospital...Findings published in a paper that is currently undergoing peer review and accessible on MedRXIV, conclude that a panel of two Nu.Q® nucleosome quantification assays (H3.1 and H3K27Me3) showed a diagnostic sensitivity of 92% and a Positive Predictive Value of 89% in identifying cancerous nodules when used in combination with LDCT screening."