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TEST:
Mammostrat® Breast Cancer Recurrence Assay

Company:
Cigna
Type:
Laboratory Developed Test

Details

Evidence
News
The Mammostrat® Breast Cancer Recurrence Assay is an immunohistochemical (IHC) assay that measures levels of five proteins in tumor tissue associated with risk of breast cancer recurrence. It is used in people with newly diagnosed, early stage breast cancer. The assay looks at five proteins and determines their expression levels in the tumor. The expression levels of these five markers are thought to influence whether the tumor will metastasize, increasing the patient’s chance of recurrence. These levels are then translated into a risk index, given as a percent chance of recurrence over 10 years
Cancer:
Breast Cancer
Gene:
CEACAM5 (CEA Cell Adhesion Molecule 5), NDRG1 (N-Myc Downstream Regulated 1), SLC7A5 (Solute Carrier Family 7 Member 5), TP53 (Tumor protein P53), TRMT2A (TRNA Methyltransferase 2 Homolog A)
Method:
Immunohistochemistry (IHC)