LymphoTrack TRB Assay – MiSeq represents a significant improvement over existing clonality assays using fragment analysis as it efficiently detects the majority of TRB gene rearrangements using a single multiplex master mix, and at the same time, identifies the DNA sequence specific for each clonal gene rearrangement. Therefore, this assay has two important and complementary uses: it both aids in the detection of initial clonal populations and identifies sequence information required to track those clones in subsequent samples.