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9ms
EGFR Exon 20 Insertion Mutations in NSCLC: The Need for Accurate Naming Conventions and Implications for Personalized Therapy (IASLC-WCLC 2023)
This study investigated the distribution of EGFR E20ins in the Asian population, with p.A767_V769dup and p.S768_D770dup being the most frequently observed mutations. Since some studies have reported single EGFR E20ins sequences using different names, it is important to be cautious when describing EGFR E20ins. To ensure comprehensive coverage in real-world settings, each method used for the detection of EGFR E20ins must be annotated according to the HGVS nomenclature.
EGFR exon 20
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EGFR (Epidermal growth factor receptor)
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EGFR mutation • EGFR exon 20 insertion • EGFR exon 20 mutation • EGFR A767_V769dup • EGFR S768_D770dup
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cobas® EGFR Mutation Test v2 • Oncomine™ Dx Target Test • Droplex EGFR Mutation Test v2 • GenesWell ddEGFR Mutation Test
over1year
Gencurix, registered a domestic patent for IVD digital PCR lung cancer diagnosis technology (Gencurix Press Release)
"Gencurix...announced...that it has registered a domestic patent for a 'composition and kit for detecting epithelial growth factor receptor gene mutation' related to lung cancer companion diagnosis...The Geneswell ddEGFR mutation test developed based on this patent is the world’s first licensed and sold product based on the digital PCR platform."
Patent
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GenesWell ddEGFR Mutation Test