EpiHera starts with the collection of a cervical swab, the same type of sample that is used in cervical cancer screening. Genomic DNA is then extracted and undergoes bisulfite conversion, where unmethylated cytosine is converted to uracil but methylated cytosine remains intact. This is followed by real-time PCR to detect hypermethylated CDO1 and CELF4. The test takes about six hours to perform with another day for the sample collection.
Cancer:
Endometrial Cancer
Gene:
CDO1 (Cysteine Dioxygenase Type 1), CELF4 (CUGBP Elav-Like Family Member 4)
CDO1 (Cysteine Dioxygenase Type 1), CELF4 (CUGBP Elav-Like Family Member 4)