TEST:

DetermaIO™

DetermaIO™ is a 27-target multivariate gene expression test performed on FFPE biopsy specimens that measures the presence of subtypes of infiltrating inflammatory cells, and the presence or absence of a differentiated stromal microenvironment. DetermaIO’s proprietary algorithm combines mRNA gene expression data and interprets the physiology of both the tumor and its surrounding micro-environment in order to predict the response to immuno-oncology therapies. Data supporting a strong association with response to checkpoint inhibitors has been shown in non-small cell lung cancer (NSCLC). The assay is currently offered for pharma service research only as a CLIA-certified real time PCR LDT from our CAP-accredited laboratory, or as an in silico interpretation of whole transcriptome RNA data.