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Company:
HiloProbeType:
CE Marked
In the ColoNode® kit six target genes are analyzed. Four of the genes are expressed in colorectal cancer epithelial cells, namely CEACAM5, KLK6, SLC35D3 and MUC2, and one biomarker, POSTN, is expressed in tumor associated fibroblasts. None of the genes are expressed in immune cells making them suitable for analysis of lymph node samples. 18S rRNA is expressed in all cell types and is analyzed for normalization and as a positive control for total-RNA suitable for real-time, quantitative RT-PCR, i.e. the technology used in the ColoNode® kit.
Cancer:
Colorectal Cancer
Gene:
CEACAM5 (CEA Cell Adhesion Molecule 5), KLK6 (Kallikrein Related Peptidase 6), MUC2 (Mucin 2), POSTN (Periostin), SLC35D3 (Solute Carrier Family 35 Member D3)
CEACAM5 (CEA Cell Adhesion Molecule 5), KLK6 (Kallikrein Related Peptidase 6), MUC2 (Mucin 2), POSTN (Periostin), SLC35D3 (Solute Carrier Family 35 Member D3)
Method:
RT-PCR
