Postoperative ctDNA monitoring using a CRC-specific epigenetic biomarker-based digital PCR assay is a promising strategy for recurrence prediction and personalized clinical management of CRC through early detection of minimal residual disease (MRD).
5 months ago
Clinical • Surgery • Minimal residual disease • Circulating tumor DNA • Epigenetic controller
"Gencurix will disclose two colorectal cancer clinical research results using its self-developed molecular diagnostic test method at the 2024 American Society of Clinical Oncology (ASCO) annual conference held on May 31."
5 months ago
Clinical data
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COLO eDX • Droplex BRAF Mutation Test • Droplex KRAS Mutation Test
"Gencurix...announced...that it had published a study showing that early colorectal cancer detection tests predicted colorectal cancer recurrence with 100% sensitivity prior to imaging tests...Gencurix utilized COLO eDX, an early detection test for colorectal cancer, to treat microscopic residual cancer after surgery..."
"Gencurix announced...that it will present the research results of 'Colloidex', an early detection test for colorectal cancer, at the American Association for Cancer Research (AACR)...Gencurix will present the results of a study on the correlation between micro-survival cancer (MRD) and recurrence after colorectal cancer surgery using Colloid X."
We have developed and validated the qualitative detection of methylation status of the bisulfite-converted target region in cfDNA. Further studies are warranted to evaluate the impact of COLO eDx on recurrence in a larger cohort of CRC patients.
over 1 year ago
Clinical • Circulating tumor DNA • Epigenetic controller