RNA-based, DNA methylation-based, protein-based, and ctDNA-based assays showed promise for UTUC diagnosis and risk stratification. However, the current evidence is limited, with few validated studies. Large prospective cohorts and biomarker-driven interventional trials are needed before clinical integration.
2 days ago
Review • Journal
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BIRC5 (Baculoviral IAP repeat containing 5) • GDF15 (Growth differentiation factor 15) • TMEFF2 (Transmembrane Protein With EGF Like And Two Follistatin Like Domains 2)