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our Premium Content: News alerts, weekly reports and conference plannersTEST:Aventa FusionPlus Test
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Company:
Aventa GenomicsType:
Laboratory Developed Test
The Aventa FusionPlus test detects gene fusions, translocations, and other rearrangements across 361 genes in formalin-fixed, paraffin embedded (FFPE) tumor tissue. 3D genomics reveals variants that conventional RNA and FISH testing should find but didn’t, plus variants with breakpoints that RNA sequencing can not find.
Cancer:
Solid Tumor
Gene:
ABL1 (ABL proto-oncogene 1), AKT1 (V-akt murine thymoma viral oncogene homolog 1), ARID1A (AT-rich interaction domain 1A), ATM (ATM serine/threonine kinase), ATR (Ataxia telangiectasia and Rad3-related protein), AURKA (Aurora kinase A)
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ABL1 (ABL proto-oncogene 1), AKT1 (V-akt murine thymoma viral oncogene homolog 1), ARID1A (AT-rich interaction domain 1A), ATM (ATM serine/threonine kinase), ATR (Ataxia telangiectasia and Rad3-related protein), AURKA (Aurora kinase A), BARD1 (BRCA1 Associated RING Domain 1), BCL2 (B-cell CLL/lymphoma 2), BRCA1 (Breast cancer 1, early onset), BRCA2 (Breast cancer 2, early onset), BRIP1 (BRCA1 Interacting Protein C-terminal Helicase 1), CCND3 (Cyclin D3), CDK4 (Cyclin-dependent kinase 4), CDK6 (Cyclin-dependent kinase 6), NRAS (Neuroblastoma RAS viral oncogene homolog), NTRK1 (Neurotrophic tyrosine kinase, receptor, type 1), NTRK2 (Neurotrophic tyrosine kinase, receptor, type 2), NTRK3 (Neurotrophic tyrosine kinase, receptor, type 3), PD-L1 (Programmed death ligand 1), PIK3CA (Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha), PIK3CB (Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta), PTCH1 (Patched 1), USP6 (Ubiquitin Specific Peptidase 6)
Method:
Next-Generation Sequencing (NGS)
