AnchorIRIS™ assay is a highly sensitive, targeted DNA methylation sequencing technique for analysing the methylation status in cfDNA. With the ultrasensitive AnchorIRIS™ assay, we can measure the methylation status of lower-input cfDNA while maintaining sufficient diversity and sensitivity. The AnchorIRIS™ assay demonstrated a very low limit of detection and limited amounts of input cfDNA (ranging from 1 to 10 ng), facilitating the use of cfDNA as a diagnostic biomarker from a typical 10 mL blood draw.
Cell-free DNA methylation (cfDNA)