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    GENE:

    ZNF346 (Zinc Finger Protein 346)

    i
    Other names: ZNF346, Zinc Finger Protein 346, JAZ, Zfp346, Just Another Zinc Finger Protein, Double-Stranded RNA-Binding Zinc Finger Protein JAZ
    2ms
    Uterine Fibroids-Associated GWAS Loci and the Risk of Arterial Hypertension: A Pilot Study. (PubMed, Front Biosci (Schol Ed))
    To our knowledge, this is the first study to explore the genetic overlap between UFs and AH, providing novel molecular evidence for shared pathophysiological pathways. Our findings support the concept of a common genetic predisposition underlying both conditions and may inform new directions for integrated reproductive and cardiovascular health strategies.
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    ZNF346 (Zinc Finger Protein 346)
    1year
    GWAS-Significant Loci and Uterine Fibroids Risk: Analysis of Associations, Gene-Gene and Gene-Environmental Interactions. (PubMed, Front Biosci (Schol Ed))
    Bioinformatics analysis showed that GWAS SNPs are involved in the molecular mechanisms of UF mainly through the regulation of vasculogenesis, cell proliferation, apoptosis, DNA damage, inflammation, hypoxia, steroid hormone metabolism, cell signaling, organ formation.
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    SIRT3 (Sirtuin 3) • SYNE1 (Spectrin Repeat Containing Nuclear Envelope Protein 1) • ZNF346 (Zinc Finger Protein 346)