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    BIOMARKER:

    ZG16B positive

    i
    Other names: ZG16B, Zymogen Granule Protein 16B, HRPE773, PRO1567, JCLN2, Jacalin-Like Lectin Domain Containing 2, Zymogen Granule Protein 16 Homolog B, Pancreatic Adenocarcinoma Upregulated Factor, Zymogen Granule Protein 16 Homolog B (Rat), Endocrine And Exocrine Protein, EECP, PAUF
    Entrez ID:
    124220
    Related biomarkers:
    Expression
    over3years
    First-in-class monoclonal antibody (mAb) PBP1510 targeting pancreatic adenocarcinoma upregulated factor (PAUF) for pancreatic cancer (PC) treatment: Preclinical perspectives. (ASCO 2022)
    The efficacy and safety data presented here, along with the data from in vivo mouse studies demonstrating superior anti-tumour activity of PBP1510 treatment, support further clinical development of PBP1510 as a novel anti-cancer agent to treat PAUF-positive PC. The pivotal step of advancing PBP1510 into initial human studies is now in progress.
    Preclinical
    |
    ZG16B (Zymogen Granule Protein 16B)
    |
    ZG16B positive
    |
    ulenistamab (PBP1510)