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    DRUG:

    ZFN modified T cell (SB-313)

    i
    Other names: SB-313, SB-313-xTZ, SB 313 xTZ, zetakine engineered T-cell therapy, GRm13Z40-2
    Associations

    News

    Trials
    Company:
    Sangamo Therap
    Drug class:
    Immunomodulator, Cytotoxic T lymphocyte stimulant
    Related drugs:
    Associations

    News

    Trials
    almost3years
    Off-the-shelf, Steroid Resistant, IL13Rα2-Specific CAR T Cells for Treatment of Glioblastoma. (PubMed, Neuro Oncol)
    This first-in-human experience establishes a foundation for future adoptive therapy studies using off-the-shelf, zinc-finger modified and/or glucocorticoid resistant CAR T cells.
    Journal • CAR T-Cell Therapy
    |
    IL2 (Interleukin 2) • IL13RA2 (Interleukin 13 Receptor Subunit Alpha 2) • IL13 (Interleukin 13)
    |
    dexamethasone • Proleukin (aldesleukin) • ZFN modified T cell (SB-313)