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BIOMARKER:

ZBTB16-RARA fusion

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Other names: ZBTB16, Zinc Finger And BTB Domain Containing 16, Zinc Finger Protein 145 (Kruppel-Like, Expressed In Promyelocytic Leukemia), Zinc Finger And BTB Domain-Containing Protein 16, Promyelocytic Leukaemia Zinc Finger, Zinc Finger Protein PLZF, ZNF145, PLZF, Promyelocytic Leukemia Zinc Finger Protein, Zinc Finger Protein 145, RARA, Retinoic Acid Receptor Alpha, Nuclear Receptor Subfamily 1 Group B Member 1, RAR-Alpha, NR1B1, Nucleophosmin-Retinoic Acid Receptor Alpha Fusion Protein NPM-RAR Long Form,
Entrez ID:
Related biomarkers:
2years
Journal
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ZBTB16 (Zinc Finger And BTB Domain Containing 16)
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ZBTB16-RARA fusion
over3years
Mutational profile of ZBTB16-RARA-positive acute myeloid leukemia. (PubMed, Cancer Med)
Our data suggest the association of mutations of the ARID1A gene and of the other members of the SWI/SNF chromatin remodeling complexes with ZBTB16-RARA+AMLs, where they may support the peculiar disease phenotype.
Journal
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ARID1A (AT-rich interaction domain 1A) • SMARCA4 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily A, member 4) • ARID2 (AT-Rich Interaction Domain 2) • ZBTB16 (Zinc Finger And BTB Domain Containing 16)
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ARID1A mutation • SMARCA4 mutation • RARA positive • ZBTB16-RARA fusion