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DRUG:

zansecimab (LY3127804)

i
Other names: LY 3127804, LY3127804
Associations
Trials
Company:
Eli Lilly
Drug class:
Angiopoietin 2 inhibitor
Associations
Trials
over4years
First-in-human, dose-escalation, phase 1 study of anti-angiopoietin-2 LY3127804 as monotherapy and in combination with ramucirumab in patients with advanced solid tumours. (PubMed, Br J Cancer)
LY3127804 monotherapy and its combination with ramucirumab are well tolerated. LY3127804 20 mg/kg was the recommended Phase 2 dose.
Clinical • P1 data • Journal • Combination therapy
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ANGPT2 (Angiopoietin 2)
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zansecimab (LY3127804)