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DRUG:

YQ23

i
Other names: YQ23, YQ-23, YQ 23
Associations
Trials
Company:
New Beta Innovation
Drug class:
Oxygen carrier
Associations
Trials
2years
A Safety Study of YQ23 in Advanced Solid Tumors Patients (clinicaltrials.gov)
P1, N=3, Terminated, New Beta Innovation Limited | N=30 --> 3 | Trial completion date: Dec 2024 --> Jul 2023 | Active, not recruiting --> Terminated; Due to business decision
Enrollment change • Trial completion date • Trial termination
|
Keytruda (pembrolizumab) • YQ23
2years
YAN: YQ23 Study in Patients With Critical Limb Ischaemia (clinicaltrials.gov)
P1/2, N=5, Terminated, New Beta Innovation Limited | Phase classification: P1b/2a --> P1/2 | N=51 --> 5 | Trial completion date: Jun 2024 --> Aug 2023 | Active, not recruiting --> Terminated; Due to business decision
Phase classification • Enrollment change • Trial completion date • Trial termination
|
YQ23
almost3years
A Safety Study of YQ23 in Advanced Solid Tumors Patients (clinicaltrials.gov)
P1, N=30, Active, not recruiting, New Beta Innovation Limited | Trial completion date: Dec 2023 --> Dec 2024 | Trial primary completion date: Dec 2022 --> Jun 2024
Trial completion date • Trial primary completion date • Combination therapy • Metastases
|
Keytruda (pembrolizumab) • YQ23
4years
The anti-tumoral effects of the oxygen carrier YQ23 in a triple-negative breast cancer syngeneic model. (PubMed, Transl Cancer Res)
In concordance with the weakened immunosuppression, the inflammatory cytokine interferon γ and cytolytic granzyme B were upregulated. YQ23 treatment may be a potential therapeutic strategy to modulate the TME in TNBC.
Journal
|
CD8 (cluster of differentiation 8) • PD-1 (Programmed cell death 1) • IFNG (Interferon, gamma) • CD4 (CD4 Molecule) • GZMB (Granzyme B)
|
YQ23