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    GENE:

    VPS13D (Vacuolar Protein Sorting 13 Homolog D)

    i
    Other names: VPS13D, Vacuolar Protein Sorting 13 Homolog D, KIAA0453, Bridge-Like Lipid Transfer Protein Family Member 5D, Vacuolar Protein Sorting-Associated Protein 13D, Intermembrane Lipid Transfer Protein VPS13D, FLJ10619, BLTP5D, Vacuolar Protein Sorting 13 Homolog D (S. Cerevisiae), Vacuolar Protein Sorting 13D (Yeast), Vacuolar Protein Sorting 13D, SCAR4
    almost3years
    Apatinib combined with camrelizumab in advanced acral melanoma patients: An open-label, single-arm phase 2 trial. (PubMed, Eur J Cancer)
    Apatinib combined with camrelizumab showed manageable safety profile and reasonable anti-tumour activity in advanced acral melanoma patients as first-line therapy.
    P2 data • Clinical Trial,Phase II • Journal • PD(L)-1 Biomarker • Metastases
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    MUC16 (Mucin 16, Cell Surface Associated) • ALPK2 (Alpha Kinase 2) • SCUBE1 (Signal Peptide, CUB Domain And EGF Like Domain Containing 1) • VPS13D (Vacuolar Protein Sorting 13 Homolog D)
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    MUC16 mutation • TTN mutation
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    AiRuiKa (camrelizumab) • AiTan (rivoceranib)