Clinical • Combination therapy • PD(L)-1 Biomarker • IO biomarker
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HER-2 (Human epidermal growth factor receptor 2) • PD-L1 (Programmed death ligand 1) • CD8 (cluster of differentiation 8) • KDR (Kinase insert domain receptor) • FLT1 (Fms-related tyrosine kinase 1) • ICOS (Inducible T Cell Costimulator)
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HER-2 negative • EGFR overexpression • KDR expression • FLT1 expression • VEGFA expression + FLT1 expression + KDR expression
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Opdivo (nivolumab) • Avastin (bevacizumab) • paclitaxel