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    BIOMARKER:

    VCL overexpression

    i
    Other names: VCL, Vinculin, Metavinculin, Epididymis Secretory Sperm Binding Protein, Epididymis Luminal Protein 114, Meta-Vinculin, HEL114, CMD1W, CMH15, MVCL
    Entrez ID:
    7414
    over3years
    A nanomechanical strategy involving focal adhesion kinase for overcoming drug resistance in breast cancer. (PubMed, Nanomedicine)
    Owing to differences in FAK activation upon co-treatment with a FAK inhibitor, the drug-resistant breast cancer cells were eradicated more efficiently than invasive breast cancer cells having pro-survival activity. These findings demonstrated the potential of a novel co-treatment regimen using FAK inhibitors for overcoming drug resistance in breast cancer cells.
    Journal
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    VCL (Vinculin)
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    VCL overexpression