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    DRUG:

    silodosin

    Company:
    Generic mfg.
    Drug class:
    α1 adrenergic receptor antagonist
    10ms
    Silodosin in Retrograde Intrarenal Surgery (clinicaltrials.gov)
    P3, N=60, Completed, Ain Shams University | Enrolling by invitation --> Completed
    Trial completion
    |
    silodosin
    1year
    Silodosin vs Placebo in the Treatment of Female LUTS (clinicaltrials.gov)
    P3, N=278, Not yet recruiting, Mansoura University
    New P3 trial
    |
    silodosin
    1year
    Prophylactic Α-Blockers for Radiotherapy-Induced LUTS in Men with Prostate Cancer: A Phase III Randomized Trial Analysis. (PubMed, Int J Radiat Oncol Biol Phys)
    Prophylactic α-blocker was not effective at significantly reducing RI-LUTS in prostate cancer patients treated with EBRT. Treating patients with α-blocker at the onset of RI-LUTS will avoid unnecessary drug exposure and toxicity. There may be a benefit for prophylactic α-blocker in patients with smaller prostate. This however, needs to be further studied in a larger study.
    P3 data • Journal
    |
    silodosin
    over1year
    Prophylactic A-Blockers for Radiotherapy-Induced Lower Urinary Tract Symptoms in Men with Prostate Cancer: A Phase III Randomized Trial. (PubMed, Cancers (Basel))
    Prophylactic α-blockers were not effective at significantly reducing RI-LUTSs in prostate cancer patients treated with EBRT. Treating patients with α-blockers at the onset of RI-LUTSs will avoid unnecessary drug exposure and toxicity.
    P3 data • Journal
    |
    silodosin