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DRUG:

silodosin

Company:
Generic mfg.
Drug class:
α1 adrenergic receptor antagonist
10d
Comparative Study of Use of Alpha-Blockers to Treat Symptoms in Prostate Cancer Patients Undergoing Radiation Therapy (clinicaltrials.gov)
P3, N=148, Completed, Sir Mortimer B. Davis - Jewish General Hospital | Recruiting --> Completed
Trial completion
|
silodosin
22d
New P3 trial
|
silodosin
11ms
Silodosin in Retrograde Intrarenal Surgery (clinicaltrials.gov)
P3, N=60, Completed, Ain Shams University | Enrolling by invitation --> Completed
Trial completion
|
silodosin
1year
Silodosin vs Placebo in the Treatment of Female LUTS (clinicaltrials.gov)
P3, N=278, Not yet recruiting, Mansoura University
New P3 trial
|
silodosin
1year
Prophylactic Α-Blockers for Radiotherapy-Induced LUTS in Men with Prostate Cancer: A Phase III Randomized Trial Analysis. (PubMed, Int J Radiat Oncol Biol Phys)
Prophylactic α-blocker was not effective at significantly reducing RI-LUTS in prostate cancer patients treated with EBRT. Treating patients with α-blocker at the onset of RI-LUTS will avoid unnecessary drug exposure and toxicity. There may be a benefit for prophylactic α-blocker in patients with smaller prostate. This however, needs to be further studied in a larger study.
P3 data • Journal
|
silodosin
over1year
Prophylactic A-Blockers for Radiotherapy-Induced Lower Urinary Tract Symptoms in Men with Prostate Cancer: A Phase III Randomized Trial. (PubMed, Cancers (Basel))
Prophylactic α-blockers were not effective at significantly reducing RI-LUTSs in prostate cancer patients treated with EBRT. Treating patients with α-blockers at the onset of RI-LUTSs will avoid unnecessary drug exposure and toxicity.
P3 data • Journal
|
silodosin