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    BIOMARKER:

    UGT1A9 expression

    i
    Other names: UGT1A9, UDP Glucuronosyltransferase Family 1 Member A9, UDP Glycosyltransferase 1 Family, Polypeptide A9, UDP-Glucuronosyltransferase 1-9, UDP-Glucuronosyltransferase 1-I, UDP-Glucuronosyltransferase 1A9, UDPGT 1-9, UGT1-09, UGT-1I, UGT1.9, UGT1I, UDP Glucuronosyltransferase 1 Family, Polypeptide A9, UDP-Glucuronosyltransferase 1 Family Polypeptide A9s, UGT1A9S, HLUGP4, UGT1-9, UGT1AI, UGT1*9, LUGP4, UDPGT, LugP4, GNT1, UGT1
    Entrez ID:
    54600
    1year
    Sleep deprivation alters hepatic UGT1A9 and propofol metabolism in mice. (PubMed, Biochem Pharmacol)
    In conclusion, our findings suggested that SD can lead to altered drug disposition and effects in vivo, and Bmal1 plays a crucial role in the crosstalk between SD-induced circadian clock disruption and drug metabolism. It initiates a new direction for the understanding of drug efficacy and toxicity changes in SD conditions and provides a scientific basis for improving the rationality of drug use.
    Preclinical • Journal
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    ARNTL (Aryl Hydrocarbon Receptor Nuclear Translocator Like) • UGT1A9 (UDP Glucuronosyltransferase Family 1 Member A9) • NR1D1 (Nuclear Receptor Subfamily 1 Group D Member 1)
    |
    UGT1A9 expression