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GENE:

UBL4A (Ubiquitin Like 4A)

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Other names: UBL4A, Ubiquitin Like 4A, DXS254E, GDX, TMA24, GET5, MDY2, UBL4, Ubiquitin-Like Protein GDX, Ubiquitin-Like Protein 4A, Ubiquitin-Like 4, Ubiquitin-Like 4A, DX254E, G6PD
Associations
Trials
3ms
Comprehensive big data analysis reveals SLC10A3 as a potential biomarker in head and neck cancer. (PubMed, Naunyn Schmiedebergs Arch Pharmacol)
These findings establish SLC10A3 as a promising therapeutic target in HNC. Its consistent upregulation, association with poor prognosis, and potential interactions with key regulatory proteins highlight its relevance for future therapeutic strategies.
Journal
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IRAK1 (Interleukin 1 Receptor Associated Kinase 1) • UBL4A (Ubiquitin Like 4A)
8ms
The tumor promoter 12-O-tetradecanoylphorbol-13-acetate suppresses cell proliferation in metastatic melanoma through TC-PTP/PTPN2 and SH-PTP2/PTPN11. (PubMed, J Biochem)
These pathways represent previously unknown responses to TPA specific to metastatic melanoma cells. Overall, these findings may contribute to the development of new anticancer agents.
Journal
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JAK2 (Janus kinase 2) • PTPN11 (Protein Tyrosine Phosphatase Non-Receptor Type 11) • PTPN2 (Protein Tyrosine Phosphatase Non-Receptor Type 2) • UBL4A (Ubiquitin Like 4A)
over2years
Joint analysis of WES and RNA-Seq identify signature genes related to metastasis in prostate cancer. (PubMed, J Cell Mol Med)
Our study provides new molecular perspectives on PCa metastasis. The signature genes and pathways could be served as potential therapeutic targets for metastasis or cancer progression.
Journal • BRCA Biomarker
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BRCA2 (Breast cancer 2, early onset) • TTN (Titin) • CD34 (CD34 molecule) • FOXA1 (Forkhead Box A1) • AGR3 (Anterior Gradient 3, Protein Disulphide Isomerase Family Member) • SOX4 (SRY-Box Transcription Factor 4) • NCOA1 (Nuclear Receptor Coactivator 1) • SOX14 (SRY-Box Transcription Factor 14) • UBL4A (Ubiquitin Like 4A)
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TTN mutation