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TVI-Brain-1
i
Other names: TVI-Brain-1
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Company:
TVAX Biomedical
Drug class:
Immunostimulant
Related drugs:
4ms
TVI-AST-008: Study of Neoantigen-specific Adoptive T Cell Therapy for Newly Diagnosed MGMT Negative Glioblastoma Multiforme (GBM) (clinicaltrials.gov)
P2/3, N=120, Recruiting, TVAX Biomedical | Trial completion date: Mar 2026 --> Mar 2027 | Trial primary completion date: Dec 2025 --> Dec 2026
Trial completion date • Trial primary completion date
|
MGMT (6-O-methylguanine-DNA methyltransferase)
|
temozolomide • TVI-Brain-1
11ms
Study of Neoantigen-specific Adoptive T Cell Therapy for Newly Diagnosed MGMT Negative Glioblastoma Multiforme (GBM) (clinicaltrials.gov)
P2/3, N=96, Recruiting, TVAX Biomedical
Trial completion date • Trial primary completion date
|
MGMT (6-O-methylguanine-DNA methyltransferase)
|
temozolomide • TVI-Brain-1
12ms
Study of Neoantigen-specific Adoptive T Cell Therapy for Newly Diagnosed MGMT Negative Glioblastoma Multiforme (GBM) (clinicaltrials.gov)
P2/3, N=96, Recruiting, TVAX Biomedical | Phase classification: P2b --> P2/3
Phase classification
|
MGMT (6-O-methylguanine-DNA methyltransferase)
|
temozolomide • TVI-Brain-1
1year
Study of Neoantigen-specific Adoptive T Cell Therapy for Newly Diagnosed MGMT Negative Glioblastoma Multiforme (GBM) (clinicaltrials.gov)
P2b, N=96, Recruiting, TVAX Biomedical | Not yet recruiting --> Recruiting
Enrollment open
|
MGMT (6-O-methylguanine-DNA methyltransferase)
|
temozolomide • TVI-Brain-1
1year
Study of Neoantigen-specific Adoptive T Cell Therapy for Newly Diagnosed MGMT Negative Glioblastoma Multiforme (GBM) (clinicaltrials.gov)
P2b, N=96, Not yet recruiting, TVAX Biomedical | Initiation date: Jun 2023 --> Sep 2023
Trial initiation date
|
MGMT (6-O-methylguanine-DNA methyltransferase)
|
temozolomide • TVI-Brain-1
over1year
TVI-Brain-1 in Expanded Access Patient (clinicaltrials.gov)
P=N/A, Available, TVAX Biomedical
New trial
|
TVI-Brain-1
over1year
Study To Test the Safety and Efficacy of TVI-Brain-1 As A Treatment for Recurrent Grade IV Glioma (clinicaltrials.gov)
P2, N=14, Completed, TVAX Biomedical | N=86 --> 14
Enrollment change
|
TVI-Brain-1
over1year
Study of Neoantigen-specific Adoptive T Cell Therapy for Newly Diagnosed o6-methylguanine-DNA-methyltransferase (MGMT) Negative Glioblastoma Multiforme (GBM) (clinicaltrials.gov)
P2b, N=96, Not yet recruiting, TVAX Biomedical | Initiation date: Mar 2023 --> Jun 2023
Trial initiation date
|
MGMT (6-O-methylguanine-DNA methyltransferase)
|
temozolomide • TVI-Brain-1
almost2years
Study of Neoantigen-specific Adoptive T Cell Therapy for Newly Diagnosed o6-methylguanine-DNA-methyltransferase (MGMT) Negative Glioblastoma Multiforme (GBM) (clinicaltrials.gov)
P2b, N=96, Not yet recruiting, TVAX Biomedical
New P2b trial
|
MGMT (6-O-methylguanine-DNA methyltransferase)
|
temozolomide • TVI-Brain-1
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