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TUSC7 overexpression

Other names: TUSC7, Tumor Suppressor Candidate 7, LINC00902, LSAMP Antisense RNA 3, Non-Protein Coding RNA 295, LSAMP Antisense RNA 3, NONHSAG035806.2, HSALNG0028235, NCRNA00295, LSAMP-AS1, LSAMP-AS3, LOC285194, LSAMPAS3
Entrez ID:
The Biological Function of TUSC7/miR-1224-3p Axis in Triple-Negative Breast Cancer. (PubMed, Cancer Manag Res)
TUSC7 overexpression significantly promoted the sensitivity of MDA-MB-468 cells to paclitaxel and carboplatin. The low TUSC7 expression is an independent prognostic factor of poor OS of TNBC patients. TUSC7 might inhibit breast cancer cell growth and metastasis both in vitro and vivo through binding with miR-1224-3P and regulating MAPK, PI3K/AKT, and NF-κB signaling pathways.
TGFBR2 (Transforming Growth Factor Beta Receptor 2) • TUSC7 (Tumor Suppressor Candidate 7)
TUSC7 overexpression
carboplatin • paclitaxel