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    BIOMARKER:

    TRPV1 overexpression

    i
    Other names: TRPV1, Transient Receptor Potential Cation Channel Subfamily V Member 1, VR1, Vanilloid Receptor Subtype 1, Osm-9-Like TRP Channel 1, Capsaicin Receptor, OTRPC1, Transient Receptor Potential Cation Channel, Subfamily V, Member 1, Transient Receptor Potential Vanilloid 1a, Transient Receptor Potential Vanilloid 1b, Vanilloid Receptor 1, TrpV1
    Entrez ID:
    7442
    6ms
    TRPV1 inhibition suppresses non-small cell lung cancer progression by inhibiting tumour growth and enhancing the immune response. (PubMed, Cell Oncol (Dordr))
    Our study suggests that TRPV1 acts as a tumour promoter in NSCLC, mediating pro-proliferative and anti-apoptotic effects on NSCLC through IGF1R signaling and regulating GABA release to affect the tumour immune response.
    Journal
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    CD8 (cluster of differentiation 8) • CD163 (CD163 Molecule) • CD4 (CD4 Molecule) • CD86 (CD86 Molecule)
    |
    TRPV1 overexpression
    almost2years
    Optimized flow cytometric detection of transient receptor potential vanilloid-1 (TRPV1) in human hematological malignancies. (PubMed, Med Oncol)
    TRPV1 expression was increased in 8% of patients (MM = 2, B-NHL = 2). In conclusion, we provide an optimized flow cytometry method for routine expression analysis of clinical samples and show that TRPV1 is increased in a subset of patients with hematological malignancies.
    Journal
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    TRPV1 (Transient Receptor Potential Cation Channel Subfamily V Member 1)
    |
    TRPV1 overexpression