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    DRUG:

    Vyglxia (troriluzole)

    i
    Other names: BHV-4157, FC-4157
    Associations

    News

    Trials
    Company:
    Biohaven
    Drug class:
    Glutamatergic modulator
    Associations

    News

    Trials
    1m
    Troriluzole in Adult Participants With Spinocerebellar Ataxia (clinicaltrials.gov)
    P3, N=299, Active, not recruiting, Biohaven Pharmaceuticals, Inc. | Trial completion date: Oct 2025 --> Jun 2026
    Trial completion date
    |
    Vyglxia (troriluzole)
    4ms
    Efficacy and Safety Study of Adjunctive Troriluzule in Obsessive Compulsive Disorder (clinicaltrials.gov)
    P3, N=589, Completed, Biohaven Pharmaceuticals, Inc. | Active, not recruiting --> Completed
    Trial completion
    |
    Vyglxia (troriluzole)
    4ms
    Efficacy and Safety Study of Adjunctive Troriluzole in Obsessive Compulsive Disorder (clinicaltrials.gov)
    P3, N=700, Active, not recruiting, Biohaven Pharmaceuticals, Inc. | Trial completion date: Jun 2025 --> Nov 2025 | Trial primary completion date: Jun 2025 --> Nov 2025 | Recruiting --> Active, not recruiting
    Enrollment closed • Trial completion date • Trial primary completion date
    |
    Vyglxia (troriluzole)
    5ms
    GBM AGILE: A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma (clinicaltrials.gov)
    P2/3, N=1280, Recruiting, Global Coalition for Adaptive Research | Trial completion date: Jun 2028 --> Jun 2030 | Trial primary completion date: Jun 2026 --> Jun 2028
    Trial completion date • Trial primary completion date
    |
    IDH wild-type
    |
    temozolomide • Stivarga (regorafenib) • lomustine • VT1021 • AZD1390 • Hepacid (pegargiminase) • paxalisib (GDC-0084) • dianhydrogalactitol (VAL-083) • Vyglxia (troriluzole)
    5ms
    BED IN 46: Methamphetamine and Troriluzole (clinicaltrials.gov)
    P1, N=40, Recruiting, University of Kentucky | Not yet recruiting --> Recruiting
    Enrollment open
    |
    Vyglxia (troriluzole)
    7ms
    BED IN 46: Methamphetamine and Troriluzole (clinicaltrials.gov)
    P1, N=40, Not yet recruiting, University of Kentucky
    New P1 trial
    |
    Vyglxia (troriluzole)
    10ms
    Troriluzole in Adult Participants With Spinocerebellar Ataxia (clinicaltrials.gov)
    P3, N=299, Active, not recruiting, Biohaven Pharmaceuticals, Inc. | N=218 --> 299
    Enrollment change
    |
    Vyglxia (troriluzole)
    11ms
    Long-term Safety Study of Adjunctive Troriluzole in Subjects With Obsessive Compulsive Disorder (clinicaltrials.gov)
    P3, N=1200, Enrolling by invitation, Biohaven Pharmaceuticals, Inc. | Trial completion date: Jun 2025 --> Jun 2026 | Trial primary completion date: Jun 2025 --> Jun 2026
    Trial completion date • Trial primary completion date
    |
    Vyglxia (troriluzole)
    11ms
    Efficacy and Safety Study of Adjunctive Troriluzule in Obsessive Compulsive Disorder (clinicaltrials.gov)
    P3, N=700, Active, not recruiting, Biohaven Pharmaceuticals, Inc. | Recruiting --> Active, not recruiting
    Enrollment closed
    |
    Vyglxia (troriluzole)
    11ms
    Efficacy and Safety Study of Adjunctive Troriluzole in Obsessive Compulsive Disorder (clinicaltrials.gov)
    P3, N=700, Recruiting, Biohaven Pharmaceuticals, Inc. | Trial completion date: Dec 2024 --> Jun 2025 | Trial primary completion date: Dec 2024 --> Jun 2025
    Trial completion date • Trial primary completion date
    |
    Vyglxia (troriluzole)
    1year
    Trial in Adult Subjects With Spinocerebellar Ataxia (clinicaltrials.gov)
    P2/3, N=141, Completed, Biohaven Pharmaceuticals, Inc. | Active, not recruiting --> Completed
    Trial completion
    |
    Vyglxia (troriluzole)
    1year
    Real-World Data Study of Troriluzole-Treated Patients With Spinocerebellar Ataxia (SCA) Compared to a Matched Natural History Control (clinicaltrials.gov)
    P=N/A, N=909, Active, not recruiting, Biohaven Therapeutics Ltd. | Enrolling by invitation --> Active, not recruiting
    Enrollment closed
    |
    Vyglxia (troriluzole)