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    BIOMARKER:

    TROAP overexpression

    i
    Other names: TROAP, Trophinin Associated Protein, TASTIN, Trophinin-Assisting Protein (Tastin), Trophinin-Associated Protein, Trophinin-Assisting Protein
    Entrez ID:
    10024
    1year
    E2F1-induced upregulation of TROAP contributes to endometrial cancer progression. (PubMed, Histol Histopathol)
    TROAP is transcriptionally activated by E2F1 and promotes EC progression by enhancing cell proliferation, metastasis, and glycolysis. The E2F1-TROAP axis may serve as a potential therapeutic target for EC treatment.
    Journal
    |
    E2F1 (E2F transcription factor 1)
    |
    TROAP overexpression
    2years
    Integrative analysis of TROAP with molecular features, carcinogenesis, and related immune and pharmacogenomic characteristics in soft tissue sarcoma. (PubMed, MedComm (2020))
    In summary, the TROAP expression is elevated in STS tissues and cells, which is related to the poor prognosis and malignant biological behaviors of STS. It could act as a potential prognostic biomarker for diagnosis and treatment of STS.
    Journal • IO biomarker
    |
    TROAP overexpression