Oral administration of TQB3616 showed more potent antitumor activity than abemaciclib in an in vitro breast cancer xenograft model, causing significant tumor regression associated with sustained target inhibition in tumor tissue and manageable in vivo toxicity. The results of this study indicate that TQB3616 is a novel CDK4/6 inhibitor, and its highly effective antitumor activity against breast cancer is expected to yield promising therapeutic effects in clinical studies.
5 months ago
Preclinical • Journal
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ER (Estrogen receptor)
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HER-2 positive • ER positive • HR positive • HER-2 negative • ER positive + HER-2 negative