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BIOMARKER:

TPR mutation

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Other names: TPR, Translocated Promoter Region, Nuclear Basket Protein, Translocated Promoter Region (To Activated MET Oncogene), Translocated Promoter Region Protein, NPC-Associated Intranuclear Protein, Nucleoprotein TPR, Megator, Nuclear Pore Complex-Associated Protein TPR, Tumor Potentiating Region
Entrez ID:
Related biomarkers:
Associations
Trials
almost3years
Identification prognostic markers for patients with defective mismatch repair in colorectal cancer: MKI67, TPR,TCHH (AACR 2022)
MKI67, TCHH and TPR were potential prognostic markers for dMMR colorectal cancer. Based on these data and rationale, we suggest that mutations in all exons of these 3 genes should be integrated into predictive biomarker panels for patients with dMMR/MSI-H, aiming to provide more accurate guidance for the selection of personalized diagnosis.
Clinical • Mismatch repair • MSi-H Biomarker
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MSI (Microsatellite instability) • TPR (Translocated Promoter Region)
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MSI-H/dMMR • TPR mutation