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    BIOMARKER:

    TP73 overexpression

    i
    Other names: TP73, Tumor Protein P73, P73, P53-Like Transcription Factor 3, P53-Related Protein 3
    Entrez ID:
    7161
    Related biomarkers:
    Expression
    over1year
    LINC00963-FOSB-mediated transcription activation of UBE3C enhances radioresistance of breast cancer cells by inducing ubiquitination-dependent protein degradation of TP73. (PubMed, J Transl Med)
    This work demonstrates that LINC00963 induces nuclear translocation of FOSB and the consequent transcription activation of UBE3C, which enhances radioresistance of BRCA cells by inducing ubiquitination-dependent protein degradation of TP73.
    Journal • BRCA Biomarker
    |
    BRCA (Breast cancer early onset) • LINC00963 (Long Intergenic Non-Protein Coding RNA 963) • TP73 (Tumor Protein P73)
    |
    TP73 overexpression