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BIOMARKER:

TP73 overexpression

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Other names: TP73, Tumor Protein P73, P73, P53-Like Transcription Factor 3, P53-Related Protein 3
Entrez ID:
Related biomarkers:
12ms
LINC00963-FOSB-mediated transcription activation of UBE3C enhances radioresistance of breast cancer cells by inducing ubiquitination-dependent protein degradation of TP73. (PubMed, J Transl Med)
This work demonstrates that LINC00963 induces nuclear translocation of FOSB and the consequent transcription activation of UBE3C, which enhances radioresistance of BRCA cells by inducing ubiquitination-dependent protein degradation of TP73.
Journal • BRCA Biomarker
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BRCA (Breast cancer early onset) • LINC00963 (Long Intergenic Non-Protein Coding RNA 963) • TP73 (Tumor Protein P73)
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TP73 overexpression