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BIOMARKER:

TP53 P190T

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Other names: TP53, Tumor Protein P53, Cellular Tumor Antigen P53, Phosphoprotein P53, Tumor Protein P53, Antigen NY-CO-13, Transformation-Related Protein 53, Mutant Tumor Protein 53, P53 Tumor Suppressor, Tumor Suppressor P53, Tumor Protein 53, BMFS5, TRP53, BCC7, LFS1
Entrez ID:
9ms
Novel oncogenic transcriptional targets of mutant p53 in esophageal squamous cell carcinoma. (PubMed, J Cell Biochem)
The tumorigenic effects of the genes were confirmed in nude mice xenograft assays. This study has therefore identified novel oncogenic targets of "non-hotspot" mutant p53 proteins relevant for ESCC besides validating the functional heterogeneity of the spectrum of tumor-specific p53 mutations.
Journal
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TP53 (Tumor protein P53)
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TP53 mutation • TP53 expression • TP53 P190T